Man Boost

SO WHAT CAN A MAN DO?

NUTRIENTS THAT HELP LOWER ESTROGEN, BOOST TEST LEVELS, AND AID IN BRAIN HEALTH*

There are nutrients that help naturally block estrogen by two methods: 

1. By flushing chemical estrogens out through the liver (IC-3 – one of the rare ingredients that do this). 

2. By blocking the process by which your body converts testosterone to estrogen. 

Grape Seed Extract

Research shows that grapeseed extract is great at blocking aromatase (conversion of testosterone to estrogen), supports cardiovascular health and circulation, testicular health, as well as being packed with antioxidants.

(sonia et al, health effects of resveratrol: results from human intervention trials, nutrients 2018 dec; 10(12) 1892.

A 2021 randomized, double-blind, placebo-controlled trial (Nutrients) with healthy volunteers showed that 300 mg/day of GSE (Enovita) for 8 weeks significantly reduced systolic and diastolic blood pressure (by 4–6 mmHg) and improved perceived stress, likely due to enhanced circulation. Another meta-analysis (Medicine, 2016) of 16 trials with 810 participants found GSE (100–2,000 mg/day) lowered blood pressure, with the most consistent benefits at 100–800 mg/day for 8–16 weeks.

A 2006 study published in Cancer Research by Kijima et al. demonstrated that GSE contains procyanidin dimers that potently inhibit aromatase activity in a dose-dependent manner. In cell cultures (MCF-7 and SK-BR-3 breast cancer cells) and an animal model (aromatase-transfected MCF-7 breast cancer xenografts in mice), GSE reduced androgen-dependent tumor growth and suppressed aromatase expression. The study suggests GSE could lower estrogen synthesis, potentially increasing androgen precursors like testosterone.

A 2019 meta-analysis (Phytotherapy Research) of randomized trials showed GSE (150–300 mg/day) reduced LDL cholesterol, triglycerides, and total cholesterol, alongside lowering blood pressure. A small study in heavy smokers (European Journal of Clinical Nutrition, 2004) found 150 mg GSE twice daily for 4 weeks lowered LDL oxidation, a key step in atherosclerosis. 

Grape seed extract is also packed with antioxidants and reduces oxadative stress, while supporting circulation. It's a great addition to Man BOOST.

RARE

INDOLE CARBINOL 3 (IC-3)

ASSISTS IN REDUCiNG ESTROGEN LEVELS

IC-3 Is found in cruciferous vegetables. The problem is that they’re also high in fiber which can also impact testosterone levels and male hormone health. So in a rare instance, supplementing with IC-3 rather than consuming a ton of fibrous vegetables, is actually optimal for men. So how does IC-3 work?

Helps the liver metabolize and flush estrogen more quickly!

Converts strong estrogen molecules into less potent kind. This should result in reduced estrogen levels and a more favorable estradiol/estrone ratio.

In a human study conducted nearly 20 years ago, 6-7 mg/kg of IC3 per day was able to significantly increase the clearance of estrogens via urine in both, men and women.

In a human study conducted nearly 20 years ago, 6-7 mg/kg of IC3 per day was able to significantly increase the clearance of estrogens via urine in both, men and women.

Taken in its pure form you can get the anti-estrogenic properties of IC3 without the male hormone-declining properties of the fiber found in cruciferous vegetables (where IC3 comes from)!

IC-3 at 400mg retails for $60 USD

POWERFUL

BORON

PROMOTES IMPROVED MALE HORMONE LEVELS + ESTROGEN REDUCTION

Boron is a powerful substance that has been studied and shown to help improve male hormone health while also decreasing estrogen. Every man should be supplementing with boron.

Take a study from Naghii et al. researchers gave eight of their male subjects ~10 mg’s of boron supplement, every morning for 7 consecutive days. After the week had passed, the scientists compared their subjects blood results from day 1 to day 7 and found out that:

Free testosterone levels had increased by 28%

Free estrogen levels had decreased by -39%

Dihydrotestosterone (DHT) levels rose by 10%

Many inflammation biomarkers (hsCRP, TNF-α) dropped significantly

Another study looked at how boron supplementation impacts serum vitamin D levels, but on the side, they also measured free testosterone levels. After 2 months of giving their 13 subject males 6 mg’s of daily boron (calcium fructo-borate) the levels of free testosterone had increased by 29,5% on average.

Boron is one of the best micronutrients there is on the planet for assisting male hormone production in men. Rarely used in supplement form though it should be a staple.

POWERFUL

ZINC PICOLINATE

Zinc, especially in its highest quality form - picolinate - can do wonders for male testosterone levels by increasing testosterone and reducing estrogen.

During strenuous exercise, elite wrestlers who supplemented with 3mg/kg of zinc daily for a month, were found of having significantly higher testosterone and thyroid hormone levels when compared to placebo group which saw steady decreases in both of the hormones due to excessive workload.

Another study with 10 young “sedentary male volunteers” in 2007 using the same dosage of zinc for the same duration of time. The men were subjected to “fatiguing bicycle exercise” during those 4-weeks and as in their previous study, zinc supplementation was able to maintain and increase total and free testosterone levels, as well as thyroid hormones when compared to a placebo pill.

Another study consisting of 37 infertile-subjects had the men take an undisclosed amount of zinc for 6-months and noted that the men who had testosterone levels on the lower end (less than 480 ng/dL) noticed significant improvements in testosterone and DHT levels, whereas the men on the higher levels of testosterone (more than 480 ng/dL) noted no increases in testosterone, but still significant increases in DHT levels. On an even more positive note, Nine of the subjects were able to conceive a child during the study period.

Another study in vitro found that supplementing with zinc reduced the activity of the female-hormone estrogen towards it receptors by 57%

From a quality standpoint, zinc picolinate is better absorbed than zinc citrate, oxide, or any other form of the supplement, which is why I chose the more expensive, higher quality zinc picolinate. Zinc picolinate retails for $59 USD at 15mg