Resveratrol: Estrogen Blocker, Brain Protector, and Fountain of Youth?
Nov 20, 2019
Depending on where you get your information, resveratrol can be called the fountain of youth, a powerful testosterone booster, or just something that you find in very small amounts in wine that won't really do anything great in your own body.
So what's the truth?
You'll find that in the following article.
We'll cover:
- Resveratrol and the fountain of youth
- Resveratrol and testosterone (and estrogen)
- Resveratrol and effectiveness (how much do you need/best form)
So, is resveratrol really a 'fountain of youth' supplement?
What is Resveratrol?
Resveratrol is found in the skin of grapes. It's the 'beneficial' phenol found in red wine. Oddly enough, it's actually an antioxidant phytoalexin, or a plant-toxin that's created as a defence mechanism against toxins.
The issue, that we'll see later, is that it's not easily absorbed by the body.
So many of the tests that show positive results on the brain, bloodflow, testosterone-enhancement, and estrogen reduction use very high doses (unreasonably high for human consumption).
Though, there is a work-aroun - more on that later...
Resveratrol: the fountain of youth?
Resveratrol can cross the mammalian blood brain barrier, and incorporate itself into brain tissue. "This study demonstrated for the first time that it, a polyphenolic antioxidant, can cross the blood-brain barrier and exert protective effects against cerebral ischemic injury."
This study also showed an increase in blood flow in humans.
This study on age-accelerated rats showed that "resveratrol prevents Alzheimer's markers and increases life span".
This study, this study, and this study, showed that it does have neuroprotective effects (protecting neurons from delayed cell death).
In short, more research needs to be done, and ideally done with a form of resveratrol other than trans-resveratrol (we'll talk about the other form later), but, it does appear to be very healthy for brain health, longevity, and as a defense against Alzheimer's and dementia.
Increasing blood flow is also important for longevity, and a lot of research has been done on resveratrol being a long-term anti-obesity agent, likely increasing metabolic rate.
All-in-all, resveratrol is great for your brain and body, your overall health, but drinking red wine is far from the best way to get your daily dose of this phenol, and most supplements don't contain nearly enough of it in an absorbable amount to have an effect.
Resveratrol and Testosterone
Resveratrol is very powerful (assuming you're using the proper dose in an absorbable form) when it comes to increasing testosterone and blocking estrogen, namely blocking aromatase, which is the precursor to estrogen, and aiding in the conversion of cholesterol into testosterone in the testes.
It blocks aromatase, which is the precursor to estrogen and the process by which testosterone is converted into estrogen in the body (show in this study, this study, and this study).
Resveratrol can increase the conversion of cholesterol to testosterone in the testes by increasing the amount of protein sTAR cells.
In short, definitely supplement with it if you're looking to increase your testosterone levels by way of blocking your testosterone from being converted into estrogen.
The Problem with Resveratrol (and the solution)
The issue with resveratrol is that it has insanely low bioavailability - that is, it takes up to 5 grams for our bodies to see the benefits of resveratrol. so, when consuming wine or eating grapes, you're not going to get enough of it to do any good.
There is a form of it (resveratrol Vesisorb®) that's been shown to be 100x more absorbable than trans-resveratrol, the form you'll find in most supplements (study).
You'll find 200mg of Vesisorb® in Man Boost™.
You'll also get your full, daily amount of zinc picolinate (the highest, most absorbable form of zinc) that helps block estrogen and increase testosterone.
As well as boron, that both helps increase testosterone, DHT levels, and block estrogen.
And, finally, IC-3 at 400mg, which is a compound that flushes estrogen out through the liver.
You'll get your full daily amount of all 4 of those potent nutrients, phytochemicals, and minerals, in Man Boost (order below)...
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